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Big Questions with Cal Fussman

May 25, 2026

In an age when AI has everyone asking what's next for humans, Cal goes looking for answers. He finds them in some unexpected places. A five-year-old girl who walked through a Transylvanian forest to save her sister's life. A New York publicist who followed a hunch to Charlotte and built something nobody had ever seen...


May 18, 2026

Cal opens this deeply personal episode of Big Questions with a flood of remarkable medical breakthroughs. 3D-printed windpipes. A pancreatic cancer drug that doubles survival rates. Nanotechnology clearing toxic proteins from the body. And he explains why he's sharing them: to balance the grief of losing his friend...


May 12, 2026

A professor at an elite university noticed something alarming: every student’s work was flawless . . . and nearly identical. All of it generated by AI. So she did the unthinkable (for the students, anyway). She banned devices and allowed only pen and paper. What happened next surprised everyone, including her...


May 5, 2026

Cal stumbles on a Chinese company offering to digitally resurrect the dead for three dollars. His first thought? Larry King would have loved this. In this episode, Cal sits down with Larry King Jr. to explore what it really means to preserve a life. The stories. The voice. The questions. From Larry Sr's relentless...