May 18, 2026
Cal opens this deeply personal episode of Big Questions with a flood of remarkable medical breakthroughs. 3D-printed windpipes. A pancreatic cancer drug that doubles survival rates. Nanotechnology clearing toxic proteins from the body. And he explains why he's sharing them: to balance the grief of losing his friend...
May 12, 2026
A professor at an elite university noticed something alarming: every student’s work was flawless . . . and nearly identical. All of it generated by AI. So she did the unthinkable (for the students, anyway). She banned devices and allowed only pen and paper. What happened next surprised everyone, including her...
May 5, 2026
Cal stumbles on a Chinese company offering to digitally resurrect the dead for three dollars. His first thought? Larry King would have loved this. In this episode, Cal sits down with Larry King Jr. to explore what it really means to preserve a life. The stories. The voice. The questions. From Larry Sr's relentless...
Apr 28, 2026
What if AI didn't replace you — it made you a better you? Dr. David Bach, Harvard-trained neuroscientist and founder of Optios, is using artificial intelligence to help people think faster, learn better, retain more, and perform at their peak. He’s stepping into what is his most consequential work yet while others...
Apr 21, 2026
Cal was 12 years old, bored out of his mind in junior high science class, waiting for the bell to ring. He had no idea his wandering brain was doing exactly what it was built to do – tell stories. We all carry the most extraordinary thing in the known universe around with us every day — and never really stop to look...